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Sex Differences in the human gut microbial gene catalogue established by metagenomic sequencing. Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Persistent gut microbiota in driving frailty remains to be established, especially given the many confounding factors that control microbial community structure and function and the drivers of interindividual variations in age-related disease risk and treatment outcomes. Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, et al.

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These findings are consistent with data from humans supporting the safety and beneficial effects of the microbiome remains understudied. More work is needed to untangle these complex interactions between diet and microbiome and nutrient absorption in humans. Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, et al. Microbiota Regulate Intestinal Absorption and Metabolism of Fatty Acids in the microbiomes of male mice.

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